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Our planet's ecosystems are teeming with life! Navigate the intricate web of interactions in these intriguing articles. How do organisms relate to one another and their surroundings? Ecology Articles Our planet's ecosystems are teeming with life! Navigate the intricate web of interactions in these intriguing articles. How do organisms relate to one another and their surroundings? You may also like: Biology, Zoology Galápagos Tortoises An end at the beginning: their conservation Beavers are back in Britain The role of beavers in the ecosystem and their reintroduction in the UK. Article #3 in a series on animal conservation around the world. Pangolins in China From poached to protected. Article #4 in a series on animal conservation around the world. Gorongosa National Park, Mozambique From conflict to community. Article #5 in a series on animal conservation around the world. Wildlife corridors Why did the sloth cross the road? Meet the microbes that feed phosphorus to plants Plants need phosphorus to make biological molecules like DNA, ATP, and the phospholipid bilayers that form cell membranes How human activity impacts the phosphorus cycle Discussing eutrophication and industrial activities

Scientia News is full of STEM blogs, articles and resources freely available across the globe for students. Browse all of our fascinating content written by students and professionals showing their passion in STEM and the other sciences. Log In Welcome to Scientia News DELIVERING INFORMATIVE CONTENT Scientia News is full of STEM blogs, articles and resources freely available across the globe for students. Browse all of our fascinating content written by students and professionals showing their passion in STEM and other sciences. We hope this platform helps you discover something that inspires your curiosity, and encourages you to learn more about important topics in STEM. Meet the Official Team NAVIGATE AND CLICK THE PHOTOS BELOW TO LEARN MORE ABOUT US! To play, press and hold the enter key. To stop, release the enter key. To play, press and hold the enter key. To stop, release the enter key. To play, press and hold the enter key. To stop, release the enter key. Latest Articles ecology How human activity impacts the phosphorus cycle View More biology What are health inequalities? View More chemistry The importance of symmetry in chemistry View More pharmacology ‘The Molecule’ by Dr Rick Sax and Dr Marta New View More CONTACT CONTACT US Scientia News welcomes anyone who wants to share their ideas and write for our platform. If you are interested in realising your writing potential with us AND live in the UK; and/ or would like to give feedback: Email us at scientianewsorg@gmail.com or fill in our GET IN TOUCH form below and we'll be in contact... Follow us on our socials for the latest updates. Comment, like and share! Join our mailing list below for latest site content. You can also sign up to become a site member . SUBSCRIPTION Join our mailing list to receive alerts for new articles and other site content. Be sure to check your spam/ junk folders in case emails are sent there. Email Subscribe GET IN TOUCH First Name Last Name Email Message Send Thanks for submitting!

Most research studies are now being diverted to Antiretroviral Therapy (ART) Facebook X (Twitter) WhatsApp LinkedIn Pinterest Copy link Antiretroviral therapy: a key to helping HIV patients 09/07/25, 10:51 Last updated: Published: 12/10/24, 11:34 Most research studies are now being diverted to Antiretroviral Therapy (ART) Human Immunodeficiency Virus, commonly called HIV, is a sexually transmitted disease that affects approximately 40 million people worldwide and is mostly common in ages 15-49 years. It is spread through direct contact with the blood, semen, pre-seminal fluid, and vaginal fluids of an infected person through mucous membranes—contact with male and female genital tracks. Additionally, HIV can be spread through breast milk from mother to child—studies have shown that infants likely contract the virus when the milk makes contact with the mucous membranes of the gut. How does HIV affect immune cells? HIV is a retrovirus—enveloped RNA viruses that can evade the immune defense system and live within host cells indefinitely. To infect cells HIV uses several mechanisms to make contact with the host cell's membrane. This involves the binding of HIV envelope protein (Env) with the cell receptor CD4 of an immune cell (T-helper cells). Env then binds to a co-receptor on the surface of the cell membrane, triggering membrane fusion. Membrane fusion leads to formation of a fusion pore where HIV successfully enters into the cell's cytoplasm through. Following this, HIV converts its RNA to DNA using enzyme reverse transcriptase and then uses integrase enzymes to become a permanent part of the host cell’s DNA. This allows HIV to replicate at a rapid rate, eventually causing the cells to bloat and rupture, killing the cell all while also “hiding” from the immune defense system and going into latency. Such a process is what weakens the immune system as there is a significant depletion in T-helper cells—cells that fight off infections and diseases. The evolution of ART For the reasons above, HIV is almost impossible to cure. While research is still being conducted to find a cure for HIV, most studies are now being diverted to Antiretroviral Therapy (ART). ART is a revolutionary treatment introduced in the late 198 0s that aims to prevent transmission of HIV, prolong survival, improve immune function and increase CD4 cell count, and improve overall mortality. The first drug released in the late 1980’s was Zidovudine, a nucleoside reverse transcriptase inhibitor (NRTI) that essentially prevents HIV’s RNA from being converted to DNA. This restricted replication hence increasing T-helper cell count. However, while shown to improve the condition of HIV patients, zidovudine did not work well on its own and caused drug resistance from prolonged use. Combination therapy was later introduced where scientists discovered zidovudine to be effective when used alongside another NRTI (dideoxycytidine). This combination did improve CD4 cell count and the overall condition of most patients, not in patients with advanced HIV who had prior use of zidovudine alone. Now, several medications such as NRTIs, non-nucleoside reverse transcriptase inhibitors (NNRTIs), protease inhibitors, and integrase inhibitors have been introduced and are used in a combination of three (Triple-Drug Therapy) to help suppress viral load to undetectable levels in the blood and improve the overall quality of life for patients. Triple-drug therapy can be tailored by doctors to improve the patient's condition. HIV is a sexually transmitted, chronic condition that affects less than 1% of the world's population. There is no cure for HIV, however, treatments (ART) have been introduced to reduce the viral load of HIV as well as improve the overall quality of life of patients. Compared to the past where these medications had to be taken multiple times a day, often causing severe side effects, patients can now take just a single tablet daily. This has changed the course of HIV treatment, allowing people to live lengthy, normal lives with the disease. Written by Sherine A Latheef Related article: CRISPR-Cas9 to potentially treat HIV REFERENCES Guha D, Ayyavoo V. Innate immune evasion strategies by human immunodeficiency virus type 1. ISRN AIDS . 2013;2013:954806. Published 2013 Aug 12. doi:10.1155/2013/954806 AlBurtamani N, Paul A, Fassati A. The Role of Capsid in the Early Steps of HIV-1 Infection: New Insights into the Core of the Matter. Viruses . 2021;13(6):1161. Published 2021 Jun 17. doi:10.3390/v13061161 Pau AK, George JM. Antiretroviral therapy: current drugs. Infect Dis Clin North Am . 2014;28(3):371-402. doi:10.1016/j.idc.2014.06.001 Mayers, Douglas L. “Prevalence and Incidence of Resistance to Zidovudine and Other Antiretroviral Drugs.” The American Journal of Medicine , vol. 102, no. 5, May 1997, pp. 70–75, https://doi.org/10.1016/s0002-9343(97)00067-3 . Accessed 5 Dec. 2021. “Antiretroviral Drug Discovery and Development | NIH: National Institute of Allergy and Infectious Diseases.” Www.niaid.nih.gov , www.niaid.nih.gov/diseases-conditions/antiretroviral-drug-development#:~:text=D urable%20HIV%20Suppression%20with%20Triple%2DDrug%20Therapy&text=In %20December%201995%2C%20saquinavir%20became. CDC. “How HIV Spreads.” HIV , 14 May 2024, www.cdc.gov/hiv/causes/index.html . clinicalinfo.hiv.gov . (n.d.). Protease Inhibitor (PI) | NIH . [online] Available at: https://clinicalinfo.hiv.gov/en/glossary/protease-inhibitor-pi . www.who.int . (n.d.). HIV . [online] Available at: https://www.who.int/data/gho/data/themes/hiv-aids#:~:text=Globally%2C%2039.9 %20million%20%5B36.1%E2%80%93. Project Gallery

Pathology and emerging therapeutics Facebook X (Twitter) WhatsApp LinkedIn Pinterest Copy link Bone cancer 09/07/25, 13:27 Last updated: Published: 12/10/23, 10:38 Pathology and emerging therapeutics Introduction: what is bone cancer? Primary bone cancer can originate in any b one. However, most cases develop in the long bones of the legs or upper arms. Each year, approximately 550 new cases are diagnosed in the United Kingdom. Primary bone cancer is distinct from secondary bone cancer, which occurs when cancer spreads to the bones from another region of the body. The focus of this article is on primary bone cancer. There are several types of bone cancer: osteosarcoma, Ewing sarcoma, and chondrosarcoma. Osteosarcoma originates in the osteoblasts that form bone. It is most common in children and teens, with the majority of cases occurring between the ages of 10 and 30. Ewing (pronounced as YOO-ing) sarcoma develops in bones or the soft tissues around the bones. Like osteosarcoma, this cancer type is more common in children and teenagers. Chondrosarcoma occurs in the chondrocytes that form the cartilage. Chondrosarcoma is most common in adults between the ages of 30 and 70 and is rare in the under-21 age group. Causes of bone cancer include genetic factors such as inherited mutations and syndromes, and environmental factors such as previous radiation exposure. Treatment will often depend on the type of bone cancer, as the specific pathogenesis of each case is unknown. What is the standard treatment for bone cancer? Most patients are treated with a combination of surgical excision, chemotherapy, and radiation therapy. Surgical excision is employed to remove the cancerous bone. Typically, it is possible to repair or replace the bone, although amputation is sometimes required. Chemotherapy involves using powerful chemicals to kill rapidly growing cells in the body. It is widely used for osteosarcoma and Ewing sarcoma but less commonly used for chondrosarcomas. Radiation therapy (also termed radiotherapy) uses high doses of radiation to damage the DNA of cancer cells, leading to the killing of cancer cells or slowed growth. Six out of every ten individuals with bone cancer will survive for at least five years after their diagnosis, and many of these will be completely cured. However, these treatments have limitations in terms of effectiveness and side effects. The limitation of surgical excision is the inability to eradicate microscopic cancer cells around the edges of the tumour. Additionally, the patient must be able to withstand the surgery and anaesthesia. Chemotherapy can harm the bone marrow, which produces new blood cells, leading to low blood cell counts and an increased risk of infection due to a shortage of white blood cells. Moreover, radiation therapy uses high doses of radiation, resulting in the damage of nearby healthy tissues such as nerves and blood vessels. Taken together, this underscores the need for a therapeutic approach that is non-invasive, bone cancer-specific, and with limited side effects. miR-140 and tRF-GlyTCC Dr Darrell Green and colleagues investigated the role of small RNAs (sRNAs) in bone cancer and its progression. Through the analysis of patient chondrosarcoma samples, the researchers identified two sRNA candidates associated with overall patient survival: miR-140 and tRF-GlyTCC. MiR-140 was suggested to inhibit RUNX2, a gene upregulated in high-grade tumours. Simultaneously, tRF-GlyTCC was demonstrated to inhibit RUNX2 expression by displacing YBX1, a multifunctional protein with various roles in cellular processes. Interestingly, the researchers found that tRF-GlyTCC was attenuated during chondrosarcoma progression, indicating its potential involvement in disease advancement. Furthermore, since RUNX2 has been shown to drive bone cancer progression, the identified miR-140 and tRF-GlyTCC present themselves as promising therapeutic targets. CADD522 Dr Darrell Green and colleagues subsequently investigated the impact of a novel therapeutic agent, CADD522, designed to target RUNX2. In vitro experiments have revealed that CADD522 reduced proliferation in chondrosarcoma and osteosarcoma. However, a bimodal effect was observed in Ewing sarcoma, indicating that lower levels of CADD522 promoted sarcoma proliferation, whereas higher levels of the same drug suppressed proliferation. In mouse models treated with CADD522, there was a significant reduction in cancer volumes observed in both osteosarcoma and Ewing sarcoma. Take-home message The results described here contribute to understanding the molecular mechanisms involved in bone cancer. They highlight the anti-proliferative and anti-tumoral effects of CADD522 in treating osteosarcoma and Ewing sarcoma. Further research is necessary to fully elucidate the specific molecular mechanism of CADD522 in bone cancer and to identify potential side effects. Written by Favour Felix-Ilemhenbhio Related articles: Secondary bone cancer / Importance of calcium / Novel neuroblastoma driver for therapeutics Project Gallery

About phosphate-solubilising micro-organisms and their role in the phosphorus cycle Facebook X (Twitter) WhatsApp LinkedIn Pinterest Copy link Meet the microbes that feed phosphorus to plants Last updated: 15/01/26, 19:00 Published: 27/11/25, 08:00 About phosphate-solubilising micro-organisms and their role in the phosphorus cycle Plants need phosphorus to make biological molecules like DNA, ATP, and the phospholipid bilayers that form cell membranes. Most phosphorus on Earth is found in its most oxidised form, phosphate (PO 4 3- ). Plant roots can only absorb soluble phosphate ions, but 80% of the phosphate in soil is insoluble and therefore unavailable for plant growth. Enter phosphate-solubilising micro-organisms. What are phosphate-solubilising micro-organisms? Phosphate solubilisation is the process by which micro-organisms convert insoluble phosphorus sources, like rocks or the biomass of dead organisms, into bioavailable phosphate ions (Figure 1). Examples of phosphate-solubilising bacteria come from the genera Bacillus , Pseudomonas , Rhizobium, Escherichia , Streptomyces , and Micromonospora , as well as some cyanobacteria. Phosphate-solubilising fungi include Aspergillus , Penicillium , Mucor , Rhizopus , Rhizophagus, and Glomus . The latter two fungal genera are arbuscular mycorrhizal (AM) fungi - more on them later. The chemistry underpinning phosphate solubilisation is complex but can broadly be split into inorganic and organic processes ( Figure 1 ). Some of these inorganic and organic processes are described in the rest of this article. Solubilising inorganic phosphate Inorganic insoluble phosphate is solubilised by microbial acids. When phosphate-containing rocks like apatite are broken down by weathering, the resulting smaller rock particles enter the soil. Micro-organisms secrete organic acids – usually gluconic acid but occasionally lactic, citric, oxalic, or other acids – to solubilise these rock particles. Acids work on inorganic phosphate in two ways. Firstly, they dissolve weathered rock pieces due to their low pH. Secondly, negatively charged acid anions (lactate, citrate, etc) displace the phosphate captured by aluminium, iron, magnesium, and calcium minerals in the rock. Organic acids are just some of the chemicals secreted by microbes to solubilise inorganic phosphate. Solubilising organic phosphorus On the other hand, microbial enzymes solubilise organic phosphorus during the decomposition of organic matter. The two types of phosphate-solubilising enzymes are phosphatases, which solubilise 90% of organic phosphorus, and phytases, which solubilise the remaining 10%. Both types of enzyme break the ester bonds linking a PO 4 3- group to the rest of a biological molecule. By expressing genes encoding phytases and phosphatases, soil micro-organisms make phosphorus available for plants. Arbuscular mycorrhizae (AM) AM fungi provide plants with phosphorus in a symbiotic relationship. These fungi consist of hyphae, which are long, thin strands of cells that extend a plant’s root network and access phosphorus where roots cannot (Figure 2). AM fungi have a three-pronged approach to improving a plant’s phosphorus uptake: firstly, they absorb phosphate from the soil and give it to the plant in exchange for carbon. Secondly, they solubilise phosphate by secreting acids and phosphatases. Finally, AM fungi recruit phosphate-solubilising bacteria to the root system by feeding them sugars and amino acids. Conclusion Phosphate-solubilising bacteria and fungi provide plants with phosphorus, an essential element for making nucleic acids and ATP. Most phosphate is inaccessible to plants, locked up in rocks and biomass. By secreting organic acids and enzymes, soil micro-organisms convert this inaccessible phosphate into a form that plant roots can absorb and incorporate into their own biomass. When that plant dies, the organic phosphorus is solubilised again for another plant to use, so phosphorus never runs out. Therefore, phosphate-solubilising microbes are a small part of the invisible world that keeps our planet green. Written by Simran Patel Related article: Human activity and the phosphorus cycle REFERENCES Silva LI da, Pereira MC, Carvalho AMX de, et al. Phosphorus-Solubilizing Microorganisms: A Key to Sustainable Agriculture. Agriculture 2023; 13: 462. Pang F, Li Q, Solanki MK, et al. Soil Phosphorus Transformation and Plant Uptake Driven by Phosphate-solubilizing Microorganisms. Front Microbiol ; 15. Epub ahead of print 27 March 2024. DOI: 10.3389/fmicb.2024.1383813 . Schipanski ME, Bennett EM. Chapter 9 - The Phosphorus Cycle. In: Weathers KC, Strayer DL, Likens GE (eds) Fundamentals of Ecosystem Science (Second Edition) . Academic Press, pp. 189–213. Tian J, Ge F, Zhang D, et al. Roles of Phosphate Solubilizing Microorganisms from Managing Soil Phosphorus Deficiency to Mediating Biogeochemical P Cycle. Biology 2021; 10: 158. Project Gallery

Neuromyelitis optica is also known as Devic disease Facebook X (Twitter) WhatsApp LinkedIn Pinterest Copy link Neuromyelitis optica – how is it different to multiple sclerosis? 10/07/25, 10:25 Last updated: Published: 13/07/24, 10:56 Neuromyelitis optica is also known as Devic disease This is article no. 6 in a series on Rare Diseases. Next article: Apocrine carcinoma . Previous article: Unfolding prion diseases . If you have never heard of neuromyelitis optica (NMO), you’re not alone! NMO is a rare disease affecting the spinal cord and optic nerve. A disease is determined as rare when it affects less than 1 in 2000 people. NMO, Devic’s disease in layman’s term, is an autoimmune disease, which means the immune system fails and attacks healthy self-cells, and can be one-off or recurrent. When patients experience a NMO attack, symptoms like eye pain and weakness in limbs, caused by inflammation of the spinal cord (transverse myelitis) and optic nerve (optic myelitis), commonly occur. There is a much higher prevalence of females with NMO than males. The exact reasons are still being researched, but some suggest it could be due to hormonal, genetic, and epigenetic factors, including the gut microbiome. Currently, there is no cure to this sudden and perplexing disease, yet medication to suppress the immune system and reduce inflammation are prescribed to patients. So the question arises – what causes NMO? In short, we don’t know yet. However, we do understand that 90% of NMO cases are caused by NMO-specific antibodies against Aquaporin4 (AQP4), an intrinsic membranes protein highly concentrated in the spinal cord and the brain, specifically in astrocytes and ependymal cells lining in the ventricles. AQP4 are water-selective channels in many plasma membranes and are responsible for maintaining brain-water homeostasis. Did you know NMO is often mistaken as Multiple Sclerosis (MS)? MS is also an autoimmune system and has similar symptoms as NMO, such as vision and mobility difficulties. However, there are important differences between the two. NMO specifically targets the optic nerves and spinal cord, leading to more severe attacks that can cause blindness and paralysis if not treated promptly. On the other hand, MS affects the brain and spinal cord more diffusely. Diagnosis and treatment for NMO and MS can be quite different, making it crucial to correctly distinguish between the two conditions. Advanced techniques like MRI scans, blood tests for specific antibodies (like AQP4-IgG for NMO), and careful clinical evaluation help doctors make the right diagnosis and provide appropriate treatment. Understanding these distinctions is vital for effective management and improving the quality of life for those affected by these diseases. Written by Chloe Kam Related article: Neuroimaging REFERENCES Hor, J.Y., Asgari, N., Nakashima, I., Broadley, S.A., Leite, M.I., Kissani, N., Jacob, A., Marignier, R., Weinshenker, B.G., Paul, F., Pittock, S.J., Palace, J., Wingerchuk, D.M., Behne, J.M., Yeaman, M.R. and Fujihara, K. (2020). Epidemiology of Neuromyelitis Optica Spectrum Disorder and Its Prevalence and Incidence Worldwide. Frontiers in Neurology , 11. doi: https://doi.org/10.3389/fneur.2020.00501 . Kim, S.-M., Kim, S.-J., Lee, H.J., Kuroda, H., Palace, J. and Fujihara, K. (2017). Differential diagnosis of neuromyelitis optica spectrum disorders. Therapeutic Advances in Neurological Disorders , 10(7), pp.265–289. doi: https://doi.org/10.1177/1756285617709723 . Mader, S. and Brimberg, L. (2019). Aquaporin-4 Water Channel in the Brain and Its Implication for Health and Disease. Cells , 8(2), p.90. doi: https://doi.org/10.3390/cells8020090 . Project Gallery

Their applications and usefulness Facebook X (Twitter) WhatsApp LinkedIn Pinterest Copy link The Importance of Emojis in Healthcare 11/07/25, 10:00 Last updated: Published: 23/06/24, 09:54 Their applications and usefulness The evolution of emojis Emojis are widely used visual symbols representing people, animals, objects and more. They can convey a writer’s tones and emotions, which can help clarify the meaning of messages. This allows the writer to build a connection with the person who has received the message. Emojis originated from smileys, which evolved into emoticons and, finally, emojis. Japanese originator Shigetaka Kurita released the first set of emojis in 1999, with the word “Emoji” being a transliteration of a Japanese word, with “e” meaning “picture”, “mo” meaning “write” and “ji” meaning “character”. Emojis in healthcare Emojis can play a significant role in healthcare by improving the communication of complex health concepts effectively, offering patients greater access to healthcare. Patients with limited health literacy would benefit from health reports containing emojis, which would help them understand and interpret information better. This was proven by a study by Stonbraker, Porras and Schnall (2019), which found that 94% of patients preferred reports with emojis as it aided their understanding. For example, emojis can be helpful in the field of dermatology, where they can be used to complement information regarding things such as lesions, colours, and symptoms, allowing doctors to communicate additional information to patients alongside primary concerns. In addition, emojis can be used in public health, such as to convey information about hand hygiene and infection prevention and control. By using emojis that are related to these fields, health professionals can communicate information and remind the public (especially patients with low levels of health literacy) to protect themselves against infections and the spread of diseases. Some existing emojis can be used to illustrate certain aspects of hand hygiene, such as touching (🤝), patient (🤒), clean (✨), procedure (💉), body fluid (🗣 💦), and exposure risk (❗). Using emojis in healthcare systems, especially infection prevention and control, can improve communication among healthcare providers and receivers, therefore improving health. The future of emojis in healthcare One of the limitations of incorporating emojis into healthcare is that they are unclear. In a healthcare context, this could lead to misunderstandings and misinterpretations. Therefore, healthcare professionals must be cautious when using emojis in patient communication. Nevertheless, with clear guidelines and communication, if emojis are leveraged even more, they will play a very important role in healthcare communication, particularly in improving health literacy and access to healthcare for vulnerable patients. Due to new and evolving technology and communication, healthcare professionals also need to adapt, and using emojis could be a way this can happen. Emojis have been rapidly evolving, with new diverse and inclusive emojis continuously being introduced, such as anatomical emojis and skin tone customisations. With roughly 30 emojis being relevant to medicine — excluding generic body parts, such as the ear (👂), hand (🖐), leg (🦵), and foot (🦶) — there is potential to create more emojis related to medicine and healthcare. Researchers Debbie Lai and Shuhan He have already proposed an additional 15 medical emojis: intestines, leg cast, stomach, spine, liver, kidney, pill pack, blood bag, IV bag, CT scan, weight scale, pill box, ECG, crutches, and a white blood cell. Despite this, there is still a need for more diverse health-related emojis. This gap can be filled by the upcoming generation of students who study health sciences, as they can use their medical and digital knowledge to create emojis to communicate aspects of health care not currently represented, such as CPR, drawing blood, and more. It is important to acknowledge the limitations and potential barriers to using emojis in healthcare. For example, they could be ambiguous, leading to misunderstandings and misinterpretations. Therefore, healthcare professionals should be careful while using them in patient communication and follow any guidelines to minimise this. Conclusion Overall, emojis can have significant benefits, as they have proven to be a powerful tool in healthcare by enhancing health literacy and improving the communication of complicated health concepts to patients. Therefore, it is important to have clear guidelines on how and when to use emojis in a healthcare setting to increase their effectiveness. Health science students can contribute meaningfully to this field by proposing and creating new emojis. Written by Naoshin Haque Related article: Virtual reality in healthcare Project Gallery

The closest planet to the Sun Facebook X (Twitter) WhatsApp LinkedIn Pinterest Copy link Exploring the solar system: Mercury 09/07/25, 14:08 Last updated: Published: 27/06/23, 15:46 The closest planet to the Sun Mercury, the closest planet to the Sun, holds a significant place in our understanding of the solar system and serves as our first stepping stone in the exploration of the cosmos. Its intriguing history dates back to ancient times when it was studied and recorded by the Babylonians in their celestial charts. Around 350 BC the ancient Greeks, recognized that the celestial body known as the evening and morning star was, in fact, a single entity. Impressed by its swift movement, they named it Hermes, after the swift messenger of their mythology. As time passed, the Roman Empire adopted the Greek discovery and bestowed upon it the name of their equivalent messenger god, Mercury, a name by which the planet is known today. This ancient recognition of Mercury's uniqueness paved the way for our continued exploration and study of this fascinating planet. Mercury's evolution As Mercury formed from the primordial cloud of gas and dust known as the solar nebula, it went through a process called accretion. Small particles collided and gradually merged together, forming larger bodies called planetesimals. Over time, these planetesimals grew in size through further collisions and gravitational attraction, eventually forming the protoplanet that would become Mercury. However, the proximity to the Sun presented unique challenges for Mercury's formation. The Sun emitted intense heat and powerful solar winds that swept away much of the planet's initial atmosphere and surface materials. This process, known as solar stripping or solar ablation, left behind a relatively thin and tenuous atmosphere compared to other planets in the solar system. The intense heat also played a crucial role in shaping Mercury's surface. The planet's surface rocks melted and differentiated, with denser materials sinking towards the core while lighter materials rose to the surface. This process created a large iron-rich core, accounting for about 70% of the planet's radius. Mercury's lack of significant geological activity, such as plate tectonics, has allowed its surface to retain ancient features and provide insights into the early history of our solar system. The planet's surface is dominated by impact craters, much like the Moon. These craters are the result of countless collisions with asteroids and comets over billions of years. The largest and most prominent impact feature on Mercury is the Caloris Basin, a vast impact crater approximately 1,525 kilometres in diameter. The impact of such large celestial bodies created shockwaves and volcanic activity, leaving behind a scarred and rugged terrain. Scientists estimate that the period known as the Late Heavy Bombardment, which occurred around 3.8 to 4.1 billion years ago, was particularly tumultuous for Mercury. During this time, the inner planets of our solar system experienced a high frequency of cosmic collisions. These impacts not only shaped Mercury's surface but also influenced the evolution of other rocky planets like Earth and Mars. Studying Mercury's geology and surface features provides valuable insights into the early stages of planetary formation and the impact history of our solar system. Exploration history Our understanding of Mercury has greatly benefited from a series of pioneering missions that ventured close to the planet and provided valuable insights into its characteristics. Let's delve into the details of these key exploratory endeavours: Mariner 10 (1974-1975): Launched by NASA, Mariner 10 was the first spacecraft to conduct a close-up exploration of Mercury. It embarked on a series of three flybys, passing by the planet in 1974 and 1975. Mariner 10 captured images of approximately 45% of Mercury's surface, revealing its heavily cratered terrain. The spacecraft's observations provided crucial information about the planet's rotation period, which was found to be approximately 59 Earth days. Mariner 10 also discovered that Mercury possessed a magnetic field, albeit weaker than Earth's. MESSENGER (2004-2015): The MESSENGER mission, short for Mercury Surface, Space Environment, Geochemistry, and Ranging, was launched by NASA in 2004. It became the first spacecraft to enter into orbit around Mercury in 2011, marking a significant milestone in the exploration of the planet. Over the course of more than four years, MESSENGER conducted an extensive study of Mercury's surface and environment. It captured detailed images of previously unseen regions, revealing the planet's diverse geological features, including vast volcanic plains and cliffs. MESSENGER's data also indicated the presence of water ice in permanently shadowed craters near Mercury's poles, surprising scientists. Furthermore, the mission discovered that Mercury possessed a global magnetic field, challenging previous assumptions about the planet's magnetism. MESSENGER's observations greatly expanded our knowledge of Mercury's geology, composition, and magnetic properties. BepiColombo (2018-Present): The BepiColombo mission, a joint endeavour between the European Space Agency (ESA) and the Japan Aerospace Exploration Agency (JAXA), aims to further enhance our understanding of Mercury. The mission consists of two separate orbiters: the Mercury Planetary Orbiter (MPO) developed by ESA and the Mercury Magnetospheric Orbiter (MMO) developed by JAXA. Launched in 2018, BepiColombo is currently on its journey to Mercury, with an expected arrival in 2025. Once there, the mission will study various aspects of the planet, including its magnetic field, interior structure, and surface composition. The comprehensive data collected by BepiColombo's orbiters will contribute significantly to our knowledge of Mercury and help answer remaining questions about its formation and evolution. These missions have played pivotal roles in advancing our understanding of Mercury. They have provided unprecedented insights into the planet's surface features, composition, magnetic field, and geological history. As exploration efforts continue, we can anticipate further revelations and a deeper understanding of this intriguing world. Future exploration While significant advancements have been made in understanding Mercury, there is still much more to learn. Scientists hope to explore areas of the planet that have not yet been observed up close, such as the north pole and regions where water ice may be present. They also aim to study Mercury's thin atmosphere, which consists of atoms blasted off the surface by the solar wind. Moreover, the advancement of technology may lead to the development of innovative missions to Mercury. Concepts such as landing missions and even manned exploration have been proposed, although the challenges associated with the planet's extreme environment and proximity to the Sun make such endeavours highly demanding. Nevertheless, the quest to unravel Mercury's mysteries continues, driven by the desire to deepen our knowledge of planetary formation, evolution, and the unique conditions that shaped this enigmatic world. Exploring the uncharted areas of Mercury, particularly the north pole, holds great scientific potential. The presence of water ice in permanently shadowed regions has been suggested by previous observations, and investigating these areas up close could provide valuable insights into the planet's volatile history and the potential for water resources. Additionally, studying Mercury's thin atmosphere is of significant interest. Comprised mostly of atoms blasted off the surface by the intense solar wind, understanding the composition and dynamics of this atmosphere could shed light on the processes that shape Mercury's exosphere. In conclusion, while significant progress has been made in unravelling the mysteries of Mercury, there is still much to explore and discover. Scientists aspire to investigate untouched regions, study the planet's thin atmosphere, and employ innovative mission concepts. The future may hold ambitious missions, including landing missions and potentially even manned exploration. As our knowledge and capabilities expand, Mercury continues to beckon us with its fascinating secrets, urging us to push the boundaries of exploration and expand our understanding of the wonders of the solar system. And with that we finish our journey into the history and exploration of Mercury and will move to Venus in the next article. Written by Zari Syed Related articles: Fuel for the colonisation of Mars / Nuclear fusion Project Gallery

Understanding what goes wrong in the brain Facebook X (Twitter) WhatsApp LinkedIn Pinterest Copy link Epilepsy 101 29/04/25, 16:10 Last updated: Published: 09/10/24, 11:32 Understanding what goes wrong in the brain Epilepsy is a condition that affects millions of people worldwide, often causing unprovoked seizures due to irregular brain activity. But what exactly happens in the brain when someone has epilepsy? It is important to establish that not everyone with seizures has epilepsy. While epilepsy can start at any age, it often begins in childhood, or in people over the age of 60. Epilepsy can be due to genetic factors - 1 in 3 people with epilepsy have family history- or brain damage from causes like stroke, infection, severe head injury or a brain tumour. However, around half of epilepsy cases have an unknown cause. Now, imagine your brain as a big city with lots of lights. Each light represents a part of your brain that controls things like movement, feelings, and thoughts. Epilepsy is like when the lights in the city start flickering or shut completely. There are three main types of epilepsy, and each affects the lights in different ways: 1) Generalized epilepsy: when all the lights in the city flicker or go out at once, affecting the whole brain. There are two main kinds: Generalized Motor (Grand Mal) Seizures: Imagine the lights in the city going wild, making everything shake. This is like the shaking or jerking movements during myoclonic or tonic-clonic seizures. Generalized Non-Motor (Absence) Seizures: Picture the lights suddenly pausing, making everything freeze. During these seizures, a person might stare into space or make small, repeated movements, like lip-smacking. 2) Focal epilepsy: when only the lights in one part of the city flicker or go out. This means only one part of the brain is affected: Focal Aware Seizures: The lights flicker, but people in that part of the city know what’s happening. The person stays aware during the seizure. Focal Impaired Awareness Seizures: The lights flicker, and people lose track of what’s going on. The person might not remember the seizure. Focal Motor Seizures: Some lights flicker, causing strange movements, like twitching, rubbing hands, or walking around. Focal Non-Motor Seizures: The lights stay on, but everything feels strange, like sudden change in mood or temperature. The person might feel odd sensations without moving in unusual ways. 3) ‘Unknown’ epilepsy: ‘Unknown’ epilepsy is like a power outage where no one knows where it happened because the person was alone or asleep during the seizure. Doctors might later figure out if it's more like generalized or focal epilepsy. Some people can even have both types. But how do doctors find out if someone has epilepsy? A range of tests could be used to look at the brain’s activity and structure, including: Electroencephalogram (EEG): detects abnormal electrical activities in the brain using electrodes. This procedure can be utilised in Stereoelectroencephalography (SEEG), a more invasive method where the electrodes are placed directly on or within the brain to locate the abnormal electrical activities more precisely. Computerized Tomography (CT) and Magnetic Resonance Imaging (MRI): form images of the brain to detect abnormal brain structures such as brain scarring, tumours or damage that may cause seizures. Blood tests: test for genetic or metabolic disorders, or health conditions such as anaemia, infections or diabetes that can trigger seizures. Magnetoencephalogram (MEG): measures magnetic signals generated by nerve cells to identify the specific area where seizures are starting, to diagnose focal epilepsy. Positron emission tomography (PET): detects biochemical changes in the brain, detecting regions of the brain with lower-than-normal metabolism linked to seizures. Single-photon emission computed tomography (SPECT): identifies seizure focus by measuring changes in blood flow in the brain during or between seizures, using a tracer injected into the patient. The seizure focus in this scan is seen by an increase in blood flow to that region. So, how does epilepsy affect the brain? For most people, especially those with infrequent or primarily generalised seizures, cognitive issues are less likely compared to those with focal seizures, particularly in the temporal lobe. The following cognitive functions can be affected: Memory : seizures can disrupt the hippocampus in the temporal lobe, responsible for storing and receiving new information. This can lead to difficulties in remembering words, concepts, names and other information. Language : seizures can affect areas of the brain responsible for speaking, understanding and storing words, which can lead to difficulties in finding familiar words. Executive function: seizures can impact the frontal lobe of the brain which is responsible for planning, decision making and social behaviour, leading to challenges in interacting, organising thoughts and controlling unwanted behaviour. While epilepsy itself cannot be cured, treatments exist to control seizures including: Anti-Epileptic Drugs (AEDs): suppress the brain’s ability of sending abnormal electrical signals - effective in 70% of patients. Diet: ketogenic diets can reduce seizures in some medication- resistant epilepsies and in children as they alter the chemical activity in the brain. Surgery: 1) Resective Surgery: removal of the part of the brain causing the seizures, such as temporal lobe resection, mainly for focal epilepsy. 2) Disconnective Surgery: cutting the connections between the nerves through which the seizure signals travel in the brain, such as in corpus callosotomy, mainly for generalised epilepsy. 3) Neurostimulation device implantation (NDI): insertion of devices in the body to control seizures by stimulating brain regions to control the electrical impulses causing the seizures. This includes vagus nerve stimulation and Deep Brain Stimulation (DBS). Even though epilepsy can be challenging, many people manage it successfully with the right treatment. Continued research offers hope for even better, long lasting treatments in the future. Written by Hanin Salem Related articles: Different types of epilepsy seizures / Alzheimer's disease / Parkinson's disease / Autism REFERENCES D’Arrigo, T. (n.d.). What Are the Types of Epilepsy? [online] WebMD. Available at: https://www.webmd.com/epilepsy/types-epilepsy [Accessed 5 Aug. 2024]. Epilepsy Foundation. (n.d.). Thinking and Memory. [online] Available at: https://www.epilepsy.com/complications-risks/thinking-and-memory [Accessed 10 Aug. 2024]. GOSH Hospital site. (n.d.). Invasive EEG monitoring. [online] Available at: https://www.gosh.nhs.uk/conditions-and-treatments/procedures-and- treatments/invasive-monitoring/ [Accessed 9 Aug. 2024]. My Epilepsy Team.com. (2016). Epilepsy: What People Don’t See (Infographic) | MyEpilepsyTeam. [online] Available at: https://www.myepilepsyteam.com/resources/epilepsy-what-people-dont-see- infographic [Accessed 29 Aug. 2024]. National institute of Neurological Disorders and stroke (2023). Epilepsy and Seizures | National Institute of Neurological Disorders and Stroke. [online] www.ninds.nih.gov . Available at: https://www.ninds.nih.gov/health- information/disorders/epilepsy-and-seizures [Accessed 10 Aug. 2024]. NHS (2020). Epilepsy. [online] NHS. Available at: https://www.nhs.uk/conditions/epilepsy/ [Accessed 10 Aug. 2024]. Project Gallery

Wildlife corridors are connecting habitats previously divided by roads Facebook X (Twitter) WhatsApp LinkedIn Pinterest Copy link Wildlife corridors: why did the sloth cross the road? Last updated: 16/09/25, 16:49 Published: 06/11/25, 08:00 Wildlife corridors are connecting habitats previously divided by roads Have you ever run over an animal while driving, or had to suddenly hit the brakes so an animal could cross the road? Engineers and ecologists have come up with genius solutions, collectively called wildlife corridors, so that this happens less often. This article is about two such solutions - green bridges, which are big vegetated overpasses, and rope bridges between trees. More than just roadkill Roads threaten animals because of a concept called habitat fragmentation. This is when big animal populations are split into two smaller populations with less resources and less genetic diversity than the original populations. Animals may try to move between habitat fragments in search of new food or mates, but die trying to cross the road. Either they walk directly onto the road and collide with cars, or they cross by walking over power lines and get electrocuted. Wildlife corridors allow animals to safely walk over roads, un-doing the habitat fragmentation and reducing their chance of extinction. Wolves in Germany A 2021 study analysed the activity of animals crossing a green bridge in Germany. This bridge, one of seven in the state of Brandenburg, was built in 2012 over the important A12 highway ( Figure 1 ). Using camera footage over a year, researchers found that grey wolves were more likely to use the bridge at dusk, at night, and in the winter. The deer and wild boars eaten by wolves were also more likely to use the bridge at dusk and at night, so the presence of wolves on the bridge did not deter their prey. Since 76% of wolves in Germany die in road-related incidents, bridges like this one are crucial for effective wolf conservation. Rope bridges in Costa Rica While Germany’s wolves and deer walk straight onto roads, Costa Rica’s tree-dwelling animals cross the road using power lines. This means the tree dwellers, including monkeys and sloths, are at risk of electrocution - in fact, nearly 1000 animals died of electrocution in Costa Rica in 2018-19. To reduce this risk, Costa Ricans have built rope bridges across the country as a safer alternative for wildlife to cross roads. Most bridges consist of a single blue nylon rope ( Figure 2a ), while researchers at the University of Costa Rica built rope bridges specially designed for howler monkeys ( Figure 2b ). Howler monkeys were targeted because of their endangered status and ecological role as seed and pollen dispersers. While the specialised bridges doubled howler monkey populations between 2015 and 2021, both them and classic rope bridges were used by squirrels, opossums, and kinkajous. However, a 2021 study found that animals use telephone lines to cross roads as frequently as they use rope bridges, and telephone lines are dangerously close to power lines. Some species still are not crossing using rope bridges, many years after their construction. Although the rope bridges are helping to reduce electrocution, they are not perfect. Heathland in the UK Closer to home, a brand-new green bridge called Cockrow Bridge will soon open in Surrey ( Figure 3 ). Surrey has lost 85% of its lowland heath in the last two centuries, but Ockham and Wisley Commons continue to support rare heathland species like the nightjar and sand lizard. These two commons, on either side of the A3/M25 junction, will be connected by the Cockrow Bridge into a 3 km-long stretch. Although existing heathland needs to be destroyed for construction, tree stumps and soil from the destroyed habitat will be repurposed on the bridge. Tree stumps will provide shelter to small animals, while the soil contains native roots and seeds to kickstart the bridge ecosystem. Since the public will be allowed on this bridge, it will improve our access to green spaces and bring revenue to local organisations. Therefore, Cockrow Bridge is expected to benefit wildlife and the public. Conclusion Wildlife corridors could be an important conservation tool by undoing habitat fragmentation, reducing roadkill, and preventing electrocution on power lines. Examples in Germany and Costa Rica look promising, and a unique heathland bridge is under construction here in the UK. Green bridges and rope bridges prove that modern infrastructure does not need to harm biodiversity, and humans can coexist with nature. Written by Simran Patel Related articles: Gorongosa National Park / Protecting rock-wallabies in Australia REFERENCES The Sloth Conservation Foundation. Connected Gardens: facilitating the peaceful co-existence of sloths and people. [Internet]. [cited 2025 Apr 13]. Available from: https://slothconservation.org/what-we-do/habitat-connectivity/ Tobias N. Swinging to safety: How canopy bridges may save Costa Rica’s howlers. Mongabay Environmental News [Internet]. 2023 Feb 15 [cited 2025 Apr 13]; Available from: https://news.mongabay.com/2023/02/swinging-to-safety-how-canopy-bridges-may-save-costa-ricas-howlers/ Gilbey V, Petty R. UK’s first heathland green bridge. Proceedings of the Institution of Civil Engineers - Civil Engineering. 2024 Nov 1;177(6):99–110. Laidlaw K, Broadbent E, Eby S. Effectiveness of aerial wildlife crossings: Do wildlife use rope bridges more than hazardous structures to cross roads? Rev Biol Trop. 2021 Oct 1;69(3):1138–48. Plaschke M, Bhardwaj M, König HJ, Wenz E, Dobiáš K, Ford AT. Green bridges in a re‐colonizing landscape: Wolves ( Canis lupus ) in Brandenburg, Germany. Conservat Sci and Prac. 2021 Mar;3(3):e364. Project Gallery